You cannot apply neuro when the victim is KO'd. You would never survive any fight with Flaaaayin if he did that with KO poison at it's current timers. You would get it applied and he would happily wait until you were both at least blind and unable to walk straight before ever waking you.

I'm going to just leave it at this for now, but neuro can only be applied by weapon and contact poison (and grenade, any poison can be applied by grenade but application rates from grenade are completely awful in all situations when grenade should be UPPING the success rate in a similar fashion to weapon nick), and unless you like griefing ghosts or have planted the appropriate item on an inattentive player beforehand, contact poison isn't really viable. You might be complaining about the fact that sometimes neuro gets applied during normal melee, but normal melee poison application rates are abysmal given how quickly you need to kill most people as a poisoner.

I've been through the ringamarole with this path three times. Twice full, one hybrid. I've been on both sides. Poisoners in isolation are underpowered. It's the traps that are making everything hell because the normal disadvantage of traps (opponent's free will, complete ignorance of or potential semi-awareness of their ocation) are gone when KO poison lasts so long you can trap both sides of a 2 exit room.

Poisoners by themselves are underpowered without imm given points because you are put in a situation where you are investing in the most expensive path of any thief path with few direct damage options to actually take advantage of it. Grenade is a horrible damage option when emetic poison application rates are as low as they are from it. It is, along with trapper, somewhat dependent on area knowledge and EXTREMELY EXPENSIVE to keep yourself viable.

Also if people would actually loot and sac his ingredient bag, it would take him potentially 1-2 RL hours to become semi-viable in combat again. No one does this when they do in fact manage to down him due to his own mistakes.