My Edge Question:

I'm curious if because I choose an edge once it appears, does that limit me from another edge I may receieve later or just the edges on the list that I chose against? For instance, lets say I have a choice between Paladin edge A, B, and C. So I choose edge A. I know the B and C dissapear (because they did). But does that mean I just can no longer pick B and C or does it mean that could hamper me from getting D and E and so forth.

Hope that makes sense.