Few things.

Poisoner - outside of eating maggots (which should be fixed/removed as a viable option) I don't see what a poisoner would do that's really that nasty. They're tedious/annoying but not lethal (to my chars, recently at least, I haven't died to a poisoner since suggest pwk from Zulg's thief).

Trapper - Setting traps is a painful, expensive process that takes forever and can backfire. I'm not really worried about a trapper setting traps while he has me knocked out.

Thug - I mean they have an extra attack and parting block - which is cool, it's not going to kill me though since if I get knocked out I'm *going* to run. Unless they land blind on me while slept (easier said than done) I'm going to just rest/quaff if he doesn't open and if he opens I'm going to flee and do the same thing. Or outright run on foot. Or just kick their ass depending on what I'm playing. I've had paladins for instance who just ate cheapshots and still killed the attacker.

Binder - if they get the leg bindings on you, you walk slow as hell and it destroys your movement. The blindfold is an "easy to land" blindness on your target to prevent them from getting a potion from their container. Unbinding is very laggy (I want to say 4+ rounds). This makes it much less likely that you get away if I open backstab into chase/cheap shot. Now, if you can actually get them into a trip spam *after* opening backstab and you *still can't* kill them then it wasn't meant to be anyway and you need to loop in a better tank.