I think decent paladins and druids might eat you alive. Not a lot to stop invoker or transmuter either.

This hasn't seemed to be true for the better / gangier people with builds of this kind, but I'm pretty sure it'd be true for me playing it.

That said, I think it'd eat melee characters who aren't very good alive, and probably stack up decently against any melee character. It'd be a fairly hard character to kill.