When I had it in the past, rot still used to hit me and I still has to take anti-rot measures. As a Drow it just used to mean that by the time rot wore off I'd only got a -4 con modifier instead of a -20 or so one. I'd always keep max con from a rot-suit but the save each tick was better with the edge.

Assuming that translates to malice, you'd probably still get hit with the malice, but so better at avoiding con loss on the tick? Probably still need to ensure your con is high though to give yourself a shot at making those saves.