...and generally discomfort an enemy to nature.

A few things off the top of my head:

1. A nearby tree root trips you as you walk by - you get put into a resting position, take a small amount of damage, and are lagged a litle bit.

2. Lightning from the sky hits you (ala call lightning).

3. A tree branch whips and smacks you in the face (small damage and some lag?)

4. A snake bites your ankle (I think you get poisoned?)

That sort of thing.

In general, if you get this cast on you, you need to either get rid of it or go to a civilized location to wait it out if there is anyone chasing you. If not, you can probably just go about your business and just be annoyed for a while.

It can be especially deadly to have this plus spores plus thornheart on you - spores sap your mana steadily, thornheart inflicts steadily increasing damage, both last a long time, and neither goes away if you are just sitting at a normal civilized room.