After finally getting a new PC last month I decided to try out the Vista Business I got from my University back in the days and to be honest: Till now I still didnt regret it...
The only trouble I had was finding the correct flash tool for my motherboard, all other drivers,programs and games seem to work without any problems till now.

Vista is certainly a resource hog but as long as you throw enough hardware at it, that doesnt pose a problem. :p